Non-invasive treatment of breast cancer: Russian mammologists unveil a novel organ-sparing treatment

Professor Petr Krivorotko, Chair of the Surgery Department at the Nikolai Petrov National Medical Research Center of Oncology, will discuss the results of the clinical trial of the novel treatment on June 21 at the session titled ‘Training the breast surgeon and surgical research’.

During the clinical trial evaluating de-escalation of invasive procedures to treat breast cancer, eleven patients with Stage IB–IIB HER2-positive and triple negative breast cancer and complete clinical resolution after neoadjuvant chemotherapy received the novel treatment at the Nikolai Petrov National Medical Research Center of Oncology in 2021. A total of 200 patients are taking part in the trial which will last till 2023.

Professor Petr Krivorotko, Chair of the Surgery Department at the Nikolai Petrov National Medical Research Center of Oncology, will discuss the results of the clinical trial of the novel treatment on June 21 at the session titled ‘Training breast surgeons and surgical research’ (stream No.4).

Organ-sparing surgery is a standard of modern cancer surgery. However, the Nikolai Petrov National Medical Research Center of Oncology has decided to take a step further and completely denounced the traditional surgery altogether. The novel treatment can be used to treat patients with Stage IB–IIB HER2-positive and triple negative breast cancer and complete clinical resolution after neoadjuvant chemotherapy.

This novel treatment is based on clinical data, proving that vacuum-assisted aspiration biopsy of the tumor bed in patients with such cancers, who have responded to systemic therapy combined with radiation therapy, can be compared to the results of the combined use of organ-sparing surgery or mastectomy and post-surgery irradiation of the remaining breast tissue, but with better cosmetic and esthetic results.

So far eleven patients have undergone the new treatment at the Center. The trial is designed to last for three years and includes 200 patients who will receive the novel treatment.

‘Once the new treatment has been introduced into clinical practice, thousands of women diagnosed with breast cancer will not have to undergo surgery any more’, said Professor Krivorotko.

To learn more about this new treatment and ask us any questions about it, please, join the on-line streaming of the Training the Breast Surgeon and Surgical Research session which will take place on June 21 from 15:10 to 15:30 (Moscow Standard Time/UTC+3) (stream 4).